In the beginning of the game after Ryu, Rei, and Teepo defeat the Nue and bring some peace to the village, they are tricked by Loki into breaking into McNeil's manor to steal back the money he taxes people in the village. Ryu and Teepo enter the mansion and end up fighting 4 ghosts of past McNeil's as they progress. After meeting up with Rei on the roof and meeting the current McNeil, they battle the combined form of his ancestors and steal the tax money from him and distribute it to everyone. He would end up having the last laugh though, as everyone including Loki were unaware of his involvement with the crime organization run by Mikba. He has Balio and Sunder burn down Rei's home and ambush the party, and all 3 were presumed to be dead until Ryu encountered Balio and Sunder again on Mt. Myrneg.
In the second half of the game Ryu and Garr witness McNeil being arrested by a group of Wyndian soldiers led by Nina for his involvement with the crime organization, and he is jailed in the prison of Castle Wyndia for the remainder of the game.